Frogs exposed to PBDE flame retardants during early life developed weakened systems, a condition that could leave them vulnerable to disease, say University of Wisconsin scientists. Their study – the first of its kind – suggests that pollutants, at levels present in the environment, may be contributing to the worldwide decline of amphibian populations. These same chemicals that were used for years in upholstery foam, plastics and electronics, have also weakened immune systems of mice, mink and possibly humans.